Function temporarily disengaged : Please press CTRL + P to send to printerback to the articles pageclick here to e-mail ImpAcTAIDSback to ImpAcTAIDS home pageClick here to be taken directly to the Lancet web site
Article
 

Paying the price of HIV/AIDS-South Africa and beyond 

 
  01 September 2003 Kelly Morris  
 

The long-awaited signing of an agreement to receive US$41 million from the Global Fund for AIDS, TB, and Malaria (GFATM) represents "a turning point for South Africa", declared GFATM head Richard Feachem on August 7.
The agreement, which includes increased access to antiretroviral and tuberculosis drugs, could not be more timely since, according to a recent World Bank report, failure to rapidly step up efforts to fight HIV/AIDS could result in the economic collapse of nations such as South Africa.
Previous economic models have underestimated how HIV/AIDS decimates human capital and "weakens the ability of today's generation to pass on its skills and knowledge to the next", says co-author and World Bank economist Shantayanan Devarajan.
"In countries facing an HIV/AIDS epidemic on the same scale as South Africa, for example, if nothing is done quickly to fight their epidemic, they could face economic collapse within several generations". Despite $15 billion pledged by the US government for the next 5 years, and increased funds promised by the EU and bilateral donors, funding still falls well short of the $10 billion that UNAIDS estimates is needed this year to tackle the global epidemic.
"There is no question that we need more money for the fight", says Keith Hansen of the World Bank's AIDS control programme in Africa. "It is hollow solace to say that finally, 20 years after the start of the HIV epidemic, we have decided to run the race." Critics point out that already, US monies have been substantially cut, and now amount to less than aid to Israel allowed in the same budget.
President Bush's explanation was that programmes cannot effectively absorb more funding, while distribution mechanisms for medications are lacking. "Sadly, the President's statements are misleading regarding the capacity of affected communities to use additional resources", says Paul Zeitz of the Global AIDS Alliance. These resources are needed precisely to strengthen health-care infrastructure and improve distribution channels, he states. In another blow, the USA has limited its GFATM contributions to one-third of overall contributions to the fund.
Thus, if the EU and others don't raise $2 billion, the US contribution falls. But some donors, such as the British government, remain convinced of the need to channel substantial funds through other mechanisms, while waiting to judge the success of the fund.
Such delaying tactics could be deadly, as could a lack of secure funding.
Gorik Ooms of Me?decins sans Frontie?res, Belgium, notes that, for example, "poor countries that want to start a national HIV treatment programme need a funding source that is reliable and guarantees some continuity; they cannot start treating people now and abandon treatment in 3 years if the donor has second thoughts about it".
Moreover, says Richard Tren of Africa Fighting Malaria, a South Africa-based advocacy group, "I think there is a danger that each agency wants to do its own thing and grab its own glory-it is certainly true of malaria control. This results in bitty projects that are not necessarily based on good science or medicine".
Better cooperation within and between sectors-eg, health, water and sanitation, education-is vital, says Vicky Blagbrough of WaterAid: "There are fundamental divisions that widen the higher up the hierarchy you go. By the time you reach multilateral donor level, the divisions are chasms. This means policy decisions, implementation, funding, and research are not coordinated and thus often not cost-effective".
Previously, different donors required countries to monitor need and assess use of funds in different ways. In response, UN agencies have formed the Global AIDS Monitoring and Evaluation Team to strengthen countries' capacity for monitoring epidemics and the performance of their programmes. In addition, the World Bank is keen that countries adopt the Joint Policy Review process recently used in Kenya, a complex but transparent process that involves all stakeholders down to the smallest groups.
Despite these moves, widespread disagreement remains over how to pay for the fight. Ooms criticises "IMF and World Bank macroeconomists who continue to impose public spending caps that exclude AIDS treatment programmes". Devarajan counters that "excessive spending that exceeds revenue leads to high fiscal deficits which, in turn, cause macroeconomic crises that often hurt the poor".
In less than 3 years, virtually all of the poorest African countries that have developed a national plan have been awarded grants under the World Bank's multi-country AIDS programme, which, like the GFATM, funds public, private, and civil-society initiatives. Tren concludes that "while support from the west is important, vital even, the buck stops with African governments". At last, even South Africa has a chance to prove its critics wrong.

 
   
   
   
     
  Infectious diseases high on agenda under new WHO leadership  
  Khabir Ahmad  
  WHO's new Director-General Jong-Wook Lee says the fight against infectious diseases-especially HIV/AIDS, tuberculosis, and malaria-will be among his "highest priorities" because they affect primarily the poor. Each year these diseases cause about 25% of all deaths worldwide.
On his first day in office, Lee appointed Jack Chow , former Special Representative of the US Secretary of State for HIV/AIDS, to lead a new HIV/AIDS, tuberculosis, and malaria cluster. "The [creation of this] new position was necessary", says Elizabeth Corbett (Biomedical Research and Training Institute, Harare, Zimbabwe), because "during the last few years there has been an unprecedented increase in the priority" given to these diseases.
In his first speech as the agency's director, Lee announced that by this year's World AIDS Day, December 1, the new HIV/AIDS, tuberculosis, and malaria department will produce a global plan to provide 3 million HIV-infected people in developing countries with antiretroviral drugs by the end of 2005-what is called the "three-by-five" target.
"Setting targets can provide focus and direction: the DOTS [directly observed therapy short-course] strategy for improving tuberculosis control has provided a very clear example of how international targets and leadership can filter down to primary health-care clinic level, resulting in better management for millions of tuberculosis patients. Lee's intentions seem to be that WHO will generate a similar momentum for management of HIV/AIDS", according to Corbett.
However, Nathan Ford of Medecins Sans Frontieres (MSF) cautions that "the three-by-five target must not become another unmet UN target. It is only half the number of people with HIV/AIDS estimated to need treatment today and this number will be much greater in 2 years' time", he warns. For this plan to be realised, Ford says WHO will have to take a much stronger position on the drug price issue.
Although drug prices have come down in recent years, many patented medicines, including many antiretroviral drugs, are still prohibitively expensive. WHO will need to push the pharmaceutical industry to implement a systematic equity pricing policy and charge much less for its drugs and diagnostics.
At the same time, WHO must promote generic competition, which has brought the price of triple therapy down to under US$300 per patient per year. Carlos Correa (University of Buenos Aires, Argentina) considers the new initiative "a positive step", but warns that ensured access to all drugs could be overlooked, as recognised by the 2001 Doha declaration on the trade-related intellectual property rights (TRIPS) agreement and public health. According to Correa, actions to improve access to antimalaria, antituberculosis, and antiretroviral drugs should also include technical assistance to developing countries to effectively use the flexibilities allowed by TRIPS and promote competition as far as possible, coupled with efforts to find innovative ways of promoting research in developing countries on new cures and vaccines for the three diseases.
Josef Decosas (Health Advisor, Plan International, West Africa Region, Accra, Ghana) adds that the role of WHO should not be to get the drugs to the people who need them, but to strengthen the systems that assure control, quality, and equity of antiretroviral treatment in developing countries. "This is where today's greatest challenge lies, and these are also issues that are squarely within the mandate of WHO", he said.
Decosas agrees with Lee that the response to severe acute respiratory syndrome has contributed enormously to building and restoring the reputation of WHO. "The threat of a potentially devastating pandemic of a serious respiratory tract infection appears to have disappeared, and that WHO had a key role in bringing this about.
It underlines one of the main remits of WHO, and the Director-General's commitment to strengthening the Global Outbreak Alert and Response Network is entirely appropriate".
The WHO also plans to launch a similar initiative for malaria control.
However, one of the main challenges the new leadership faces is to find ways in which artemisinin combinations could be included in malaria-treatment protocols at country level. Several donors, including the US Agency for International Aid and the UK Department for International Development, continue to support the use of old drugs to which there are high levels of resistance. The problem is further compounded by lack of funds for all his ambitious plans. The WHO's annual budget is only US$1.1 billion. International aid for malaria control is around $100 million per year but to achieve WHO's goal-to halve malaria deaths by 2010, and to halve them again by 2015-would alone need $1.5-$2.5 billion annually, according to a study by Vasant Narasimhan (Harvard Medical School, Boston, MA, USA) and colleagues.
Lee also appointed former head of WHO communicable diseases department, David Heymann, to head the WHO effort against polio. "I am committed to an all-out assault on polio. I want to complete the eradication of this disease within my tenure as Director-General", said Lee. India, Nigeria, Pakistan, and Egyptaccounted for 99% of new cases last year. So "I am immediately upgrading WHO's capacity to support their efforts to immunise every child against polio".
 
     
Function temporarily disengaged : Please press CTRL + P to send to printerback to the articles pageclick here to e-mail ImpAcTAIDSback to ImpAcTAIDS home pageClick here to be taken directly to the Lancet web site