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The
long-awaited signing of an agreement to receive US$41 million from the
Global Fund for AIDS, TB, and Malaria (GFATM) represents "a turning
point for South Africa", declared GFATM head Richard Feachem on August
7.
The agreement, which includes increased access to antiretroviral and tuberculosis
drugs, could not be more timely since, according to a recent World Bank
report, failure to rapidly step up efforts to fight HIV/AIDS could result
in the economic collapse of nations such as South Africa.
Previous economic models have underestimated how HIV/AIDS decimates human
capital and "weakens the ability of today's generation to pass on
its skills and knowledge to the next", says co-author and World Bank
economist Shantayanan Devarajan.
"In countries facing an HIV/AIDS epidemic on the same scale as South
Africa, for example, if nothing is done quickly to fight their epidemic,
they could face economic collapse within several generations". Despite
$15 billion pledged by the US government for the next 5 years, and increased
funds promised by the EU and bilateral donors, funding still falls well
short of the $10 billion that UNAIDS estimates is needed this year to
tackle the global epidemic.
"There is no question that we need more money for the fight",
says Keith Hansen of the World Bank's AIDS control programme in Africa.
"It is hollow solace to say that finally, 20 years after the start
of the HIV epidemic, we have decided to run the race." Critics point
out that already, US monies have been substantially cut, and now amount
to less than aid to Israel allowed in the same budget.
President Bush's explanation was that programmes cannot effectively absorb
more funding, while distribution mechanisms for medications are lacking.
"Sadly, the President's statements are misleading regarding the capacity
of affected communities to use additional resources", says Paul Zeitz
of the Global AIDS Alliance. These resources are needed precisely to strengthen
health-care infrastructure and improve distribution channels, he states.
In another blow, the USA has limited its GFATM contributions to one-third
of overall contributions to the fund.
Thus, if the EU and others don't raise $2 billion, the US contribution
falls. But some donors, such as the British government, remain convinced
of the need to channel substantial funds through other mechanisms, while
waiting to judge the success of the fund.
Such delaying tactics could be deadly, as could a lack of secure funding.
Gorik Ooms of Me?decins sans Frontie?res, Belgium, notes that, for example,
"poor countries that want to start a national HIV treatment programme
need a funding source that is reliable and guarantees some continuity;
they cannot start treating people now and abandon treatment in 3 years
if the donor has second thoughts about it".
Moreover, says Richard Tren of Africa Fighting Malaria, a South Africa-based
advocacy group, "I think there is a danger that each agency wants
to do its own thing and grab its own glory-it is certainly true of malaria
control. This results in bitty projects that are not necessarily based
on good science or medicine".
Better cooperation within and between sectors-eg, health, water and sanitation,
education-is vital, says Vicky Blagbrough of WaterAid: "There are
fundamental divisions that widen the higher up the hierarchy you go. By
the time you reach multilateral donor level, the divisions are chasms.
This means policy decisions, implementation, funding, and research are
not coordinated and thus often not cost-effective".
Previously, different donors required countries to monitor need and assess
use of funds in different ways. In response, UN agencies have formed the
Global AIDS Monitoring and Evaluation Team to strengthen countries' capacity
for monitoring epidemics and the performance of their programmes. In addition,
the World Bank is keen that countries adopt the Joint Policy Review process
recently used in Kenya, a complex but transparent process that involves
all stakeholders down to the smallest groups.
Despite these moves, widespread disagreement remains over how to pay for
the fight. Ooms criticises "IMF and World Bank macroeconomists who
continue to impose public spending caps that exclude AIDS treatment programmes".
Devarajan counters that "excessive spending that exceeds revenue
leads to high fiscal deficits which, in turn, cause macroeconomic crises
that often hurt the poor".
In less than 3 years, virtually all of the poorest African countries that
have developed a national plan have been awarded grants under the World
Bank's multi-country AIDS programme, which, like the GFATM, funds public,
private, and civil-society initiatives. Tren concludes that "while
support from the west is important, vital even, the buck stops with African
governments". At last, even South Africa has a chance to prove its
critics wrong. |
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WHO's new
Director-General Jong-Wook Lee says the fight against infectious diseases-especially
HIV/AIDS, tuberculosis, and malaria-will be among his "highest priorities"
because they affect primarily the poor. Each year these diseases cause about
25% of all deaths worldwide.
On his first day in office, Lee appointed Jack Chow , former Special Representative
of the US Secretary of State for HIV/AIDS, to lead a new HIV/AIDS, tuberculosis,
and malaria cluster. "The [creation of this] new position was necessary",
says Elizabeth Corbett (Biomedical Research and Training Institute, Harare,
Zimbabwe), because "during the last few years there has been an unprecedented
increase in the priority" given to these diseases.
In his first speech as the agency's director, Lee announced that by this
year's World AIDS Day, December 1, the new HIV/AIDS, tuberculosis, and malaria
department will produce a global plan to provide 3 million HIV-infected
people in developing countries with antiretroviral drugs by the end of 2005-what
is called the "three-by-five" target.
"Setting targets can provide focus and direction: the DOTS [directly
observed therapy short-course] strategy for improving tuberculosis control
has provided a very clear example of how international targets and leadership
can filter down to primary health-care clinic level, resulting in better
management for millions of tuberculosis patients. Lee's intentions seem
to be that WHO will generate a similar momentum for management of HIV/AIDS",
according to Corbett.
However, Nathan Ford of Medecins Sans Frontieres (MSF) cautions that "the
three-by-five target must not become another unmet UN target. It is only
half the number of people with HIV/AIDS estimated to need treatment today
and this number will be much greater in 2 years' time", he warns. For
this plan to be realised, Ford says WHO will have to take a much stronger
position on the drug price issue.
Although drug prices have come down in recent years, many patented medicines,
including many antiretroviral drugs, are still prohibitively expensive.
WHO will need to push the pharmaceutical industry to implement a systematic
equity pricing policy and charge much less for its drugs and diagnostics.
At the same time, WHO must promote generic competition, which has brought
the price of triple therapy down to under US$300 per patient per year. Carlos
Correa (University of Buenos Aires, Argentina) considers the new initiative
"a positive step", but warns that ensured access to all drugs
could be overlooked, as recognised by the 2001 Doha declaration on the trade-related
intellectual property rights (TRIPS) agreement and public
health. According to Correa, actions to improve access to antimalaria, antituberculosis,
and antiretroviral drugs should also include technical assistance to developing
countries to effectively use the flexibilities allowed by TRIPS
and promote competition as far as possible, coupled with efforts to find
innovative ways of promoting research in developing countries on new cures
and vaccines for the three diseases.
Josef Decosas (Health Advisor, Plan International, West Africa Region, Accra,
Ghana) adds that the role of WHO should not be to get the drugs to the people
who need them, but to strengthen the systems that assure control, quality,
and equity of antiretroviral treatment in developing countries. "This
is where today's greatest challenge lies, and these are also issues that
are squarely within the mandate of WHO", he said.
Decosas agrees with Lee that the response to severe acute respiratory syndrome
has contributed enormously to building and restoring the reputation of WHO.
"The threat of a potentially devastating pandemic of a serious respiratory
tract infection appears to have disappeared, and that WHO had a key role
in bringing this about.
It underlines one of the main remits of WHO, and the Director-General's
commitment to strengthening the Global Outbreak Alert and Response Network
is entirely appropriate".
The WHO also plans to launch a similar initiative for malaria control.
However, one of the main challenges the new leadership faces is to find
ways in which artemisinin combinations could be included in malaria-treatment
protocols at country level. Several donors, including the US Agency for
International Aid and the UK Department for International Development, continue
to support the use of old drugs to which there are high levels of resistance.
The problem is further compounded by lack of funds for all his ambitious
plans. The WHO's annual budget is only US$1.1 billion. International aid
for malaria control is around $100 million per year but to achieve WHO's
goal-to halve malaria deaths by 2010, and to halve them again by 2015-would
alone need $1.5-$2.5 billion annually, according to a study by Vasant Narasimhan
(Harvard Medical School, Boston, MA, USA) and colleagues.
Lee also appointed former head of WHO communicable diseases department,
David Heymann, to head the WHO effort against polio. "I am committed
to an all-out assault on polio. I want to complete the eradication of this
disease within my tenure as Director-General", said Lee. India, Nigeria,
Pakistan, and Egyptaccounted for 99% of new cases last year. So "I
am immediately upgrading WHO's capacity to support their efforts to immunise
every child against polio". |
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